Genetic Mutations and impact on melanoma treatment pathways

Published Caitlin Broomhall on

This webinar aimed to empower nurses with an enhanced understanding of genetic mutations in melanoma and their implications for treatment decisions. By exploring the genetic drivers behind melanoma, nurses can play a vital role in guiding patients through the complexities of immunotherapy, targeted therapies and emerging treatments, supporting personalised care and better outcomes.

Watch on demand

Event recording

Recording guide

Explore the topics

Open the guide below to see the eight topics covered, then select any topic to open the recording at that point on YouTube in a new tab.

Show the 8 topicsHide the topics
01 Welcome and speaker introductions (opens in a new tab) 0:00 → Opens the webinar with an Acknowledgement of Country and introduces the speakers presenting on genetic mutations in melanoma. 02 Understanding genetic mutations in melanoma (opens in a new tab) 3:53 → Chromosomal alterations, germline mutations and somatic driver mutations such as BRAF, RAS, NF1 and KIT, along with their mechanisms and targeted inhibitors. 03 Tumour mutational burden and treatment sequencing (opens in a new tab) 19:04 → Tumour mutational burden's link to immunotherapy response, and why immunotherapy is typically given ahead of BRAF/MEK targeted therapy. 04 Key takeaways on targeted therapy (opens in a new tab) 22:39 → A summary of the main messages on when and how to use targeted therapy in melanoma treatment. 05 Nursing perspective: supporting patients through targeted therapy and immunotherapy (opens in a new tab) 25:07 → The nurse's role in educating, monitoring and coordinating care for patients receiving targeted therapy and immunotherapy. 06 Emerging therapies, clinical trials and patient advocacy (opens in a new tab) 28:57 → New treatment approaches, staying current with clinical trials, and the nurse's role as a patient advocate. 07 Case study: Mrs C, a BRAF-positive patient (opens in a new tab) 31:00 → A real patient case illustrating the challenges and lessons learned in managing a BRAF-positive melanoma patient on oral therapy. 08 A nurse-led pathway for optimising oral medication adherence (opens in a new tab) 34:15 → A three-step pathway tool for assessing, screening and monitoring patients to improve adherence to oral melanoma medications. 

Learning outcomes

What you will learn

After this session, nurses will be able to:

01

Explain genetic mutations in melanoma progression and treatment

Understand how genetic mutations influence the selection of targeted therapies, immunotherapy and emerging treatment options.

02

Integrate genetic mutation knowledge into nursing practice

Provide informed education and support to patients undergoing complex melanoma treatments, fostering personalised care and improved patient outcomes.

At a glance

The event in brief

Originally held

Thursday 16 January 2025

Online webinar, part of the Melanoma Nursing Webinar Program.

Who this is for

Nurses

Nurses supporting patients through melanoma treatment decisions involving genetic mutations.

Contributors

Speakers

Dr Andrea Boutros

Speaker

Dr Andrea Boutros

Medical Oncology Fellow, Melanoma Institute Australia

Dr Andrea Boutros is a Medical Oncology Fellow at Melanoma Institute Australia and a specialist in melanoma and cutaneous malignancies. With extensive experience in clinical trials, including early-phase studies, his research focuses on optimising immunotherapy, managing immune-related adverse events, and improving patient quality of life. Dr Boutros is actively involved in collaborative projects exploring the genetic and molecular drivers of melanoma, and is a member of ESMO, ASCO and the Italian Melanoma Intergroup (IMI). He is also dedicated to education, frequently engaging with multidisciplinary teams to share insights on cutting-edge melanoma therapies.

Ms Melanie Grimmer

Speaker

Ms Melanie Grimmer

Melanoma and Skin Cancer Specialist Nurse, Division Cancer and Ambulatory Support, Canberra Health Services, ACT Government

Melanie Grimmer is the Melanoma and Skin Cancer Specialist Nurse at The Canberra Hospital. Melanie has been a cancer nurse for nine years, specialising in melanoma and skin cancer for the last two. She has completed a Postgraduate Certificate in Cancer Nursing and is currently completing a Master's in Advanced Nursing and Leadership. Melanie has a keen interest in educating early-career nurses about the opportunities cancer nursing offers, with a focus on advanced practice skills, and enjoys learning innovative new treatments and applying advanced nursing to improve the patient experience. She values connecting with the community of melanoma nurses and collaborating to improve practice through a multidisciplinary approach.

Keep learning

Further resources

Screening and Genetic Testing in Melanoma (opens in a new tab) YouTube video →Genetics and Genomics of Melanoma: Current Progress and Future Directions (opens in a new tab) Genetics and Genomics of Melanoma: Current Progress and Future Directions →

This webinar was brought to you by

Melanoma Institute Logo

Resource details

genetic database
Course type
Webinars
Duration
40 mins
Price
$0.00
Curriculum Area
Prevention, screening and diagnostics
Speciality
Clinician
Nurse

This course is brought to you by

Alliance members