VCCC Alliance Precision Oncology Forum

Advances and emerging innovations in CAR-T therapy

Delivered: 17 October 2025

Advances and emerging innovations in CAR-T therapy

CAR-T therapy has become an established and transformative approach for treating several blood cancers. However, its application in solid tumours has continued to face significant challenges. Despite these hurdles, recent clinical studies and preclinical advances have offered promising new insights.

This session provided an overview of the current clinical landscape of CAR-T cell therapies, with speakers highlighting innovative strategies being developed to enhance their effectiveness in solid tumours. Emerging approaches demonstrated in preclinical models were discussed, showcasing how these advances are opening exciting new possibilities for future treatment. 

Chairs

Dr Huiling Xu
Senior Research Fellow, Peter MacCallum Cancer Centre

Dr Joep Vissers
Curation Scientist Team Leader, the University of Melbourne

Speakers

Dr Mark Dowling (recording not available)
Haematologist and Postdoctoral Fellow
Peter MacCallum Cancer Centre and Royal Melbourne Hospital

Dr Isabelle Munoz
Fundamental Cancer Researcher and Immunologist
Peter MacCallum Cancer Centre

Dr Marit Jolien van Elsas
Postdoctoral Scientist
Peter MacCallum Cancer Centre

Content warning: The VCCC Alliance Precision Oncology Forum is aimed primarily at a clinical audience and features open discussion about real cases and patients. While these cases are de-identified, the imagery, content and discussion can be graphic.